Selank – 10mg

Selank, an analog of the endogenous tetrapeptide tuftsin, is widely recognized for its potential in enhancing cognitive function, improving memory, and boosting mental clarity, often classified informally as a nootropic. Developed in the early 1990s at the Russian Academy of Sciences, Selank primarily gained attention for its anxiolytic properties, believed to be due to its modulation of neurotransmitters such as serotonin, dopamine, and GABA. This action not only reduces anxiety but also promotes a sense of calmness without inducing sedation or impairing cognitive abilities.

Intriguingly, Selank’s influence extends beyond the central nervous system, as it interacts with the immune system by affecting gene expression and modulating cytokine balance. It has shown promise in the treatment of various conditions, including anxiety disorders, depression, and cognitive impairments. While approved for treating generalized anxiety disorder in Russia and some CIS states, it remains unreviewed by the FDA for clinical use in the U.S.

Selank’s mechanisms are multifaceted. It alters the expression of GABA receptors, enhancing their affinity for GABA and thus mimicking the effects of benzodiazepines but without their side effects. It protects enkephalins, endogenous peptides involved in pain and anxiety reduction, by inhibiting enzymes that degrade them. This was evidenced in studies demonstrating its anxiolytic impact on certain mouse strains. Additionally, Selank suppresses the reproduction of the H3N2 influenza strain more effectively than traditional antiviral drugs, suggesting potential antiviral capabilities.

Clinical trials and studies have illuminated several benefits of Selank. Its anxiolytic effects are notable, with studies showing it reduces anxiety, increases enkephalin levels, and may enhance the effectiveness of other anxiety treatments. Its stress-relief potential is also significant, as it moderates stress-related hormone release and aids in stress adaptation. Furthermore, its cognitive-enhancing effects have been observed in learning-disabled rats, with improvements in learning, memory, and problem-solving skills.

Potential side effects include headaches and nausea. Nevertheless, its wide-ranging applications and ongoing research make it a compound of considerable interest in the scientific community.

For Research Use Only